Capilano University was founded in 1968, initially as a college. In 1973, the permanent campus in North Vancouver was opened. Four years later, the kálax-ay Sunshine Coast campus in Sechelt was established, and CapU Lonsdale opened in 2020.
CapU enrolls approximately 12,700 students each year, with 9,000 in for-credit programs, nearly 1,200 in non-credit courses, and 2,500 international students.
The university is named after Chief Joe Capilano, an important leader of the Squamish (Sḵwx̱wú7mesh) Nation of the Coast Salish people. The campuses are located on the traditional and ancestral territory of the Squamish, Tsleil-Waututh, Musqueam, Lil'wat, and Sechelt (shíshálh) Nations.
In 2008, the provincial government changed the institution's designation to Capilano University.